Understanding Differences Between DNA and RNA

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AP Biology › Understanding Differences Between DNA and RNA

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1

In DNA adenine (A) bonds to thymine (T) and guanine (G) bonds to cytosine (C). What is the bonding scheme in RNA?

A-U and C-G

CORRECT

A-C and G-U

0

A-G and C-U

0

A-T and C-G

0

None of these

0

Explanation

In RNA, thymine is substituted by uracil. So adenine will bond to uracil instead of thymine when RNA interacts with DNA and when RNA folds with itself to make a 3-dimensional structure.

2

All of the following bases are found in RNA except __________.

thymine

CORRECT

uracil

0

guanine

0

cytosine

0

adenine

0

Explanation

Uracil is only found in RNA under normal conditions. It replaces thymine, which is only found in DNA. Therefore, thymine, adenine, cytosine, and guanine are the bases found in DNA, and uracil, adenine, cytosine, and guanine are the bases found in RNA.

3

Which of the following molecules is not present in DNA?

Uracil

CORRECT

Thymine

0

Phosphate

0

Deoxyribose sugar

0

All of these

0

Explanation

Uracil is a nitrogenous base that is only found in single-stranded RNA—it is not found in DNA. Thymine pairs with adenine in DNA, whereas in RNA, uracil pairs with adenine.

4

Which of the following is not a true characteristic of an RNA molecule?

It contains deoxyribose sugar

CORRECT

It contains the nucleotide uracil

0

It can be single stranded

0

It can be double stranded

0

Explanation

RNA molecules are most commonly found in a single stranded form (e.g. mRNA), but they can also be found in a double stranded form (e.g. viruses). It has four base pairs—uracil, adenine, guanine, and cytosine—and a ribose sugar-phosphate backbone. DNA molecules contin a deoxyribose sugar in their sugar-phosphate backbone; thus, this answer is incorrect.

5

DNA with its associated protein scaffold forms a complex called __________.

chromatin

CORRECT

chromatid

0

centromere

0

chromosome

0

nucleotide

0

Explanation

Chromatin is the DNA-protein complex and is organized as a long, thin fiber. Chromosomes are densely-packed chromatin, wrapped around proteins called histones. The centromere is the region of a condensed chromosome that connects sister chromatids to each other, and is the site at which the spindle fibers attach during mitosis in order to move them about the cytoplasm.

6

Which of the following RNA molecules transports amino acids to ribosomes to be used to assemble the protein molecule?

tRNA

CORRECT

mRNA

0

snRNA

0

pre-mRNA

0

rRNA

0

Explanation

mRNA is messenger RNA, it carries the genetic code that determines the protein. snRNA directs splicing of pre-mRNA. tRNA transports the amino acids used for assembling proteins. rRNA is a component of ribosomes (the other component is protein). pre-mRNA- single strand of RNA processed to form mRNA.

7

Which of the following are correct regarding the central dogma of biology?

DNA directs the synthesis of mRNA, which in turn directs the production of polypeptides

CORRECT

RNA assists with the replication of DNA which encodes information for proteins

0

RNA encodes the information for the assembly of ribosomes, which are the sites of protein production

0

RNA signals DNA to activate protein production

0

Explanation

DNA encodes information for the production of messenger RNA which then interacts with the cell's protein-synthesizing machinery to produce proteins. Ribosomes are the sites of polypeptide synthesis but are not coded for by RNA. The central dogma of biology is DNA RNA protein

8

The entire collection of DNA in a cell is called the __________.

genome

CORRECT

nucleus

0

chromosome

0

DNA ladder

0

chromatin

0

Explanation

The genome is defined as the total genetic library of a cell. It is estimate that in humans, the genome codes for about 25,000 different genes.

9

Which of the following types of RNA is double stranded?

Viral RNA

CORRECT

mRNA

0

tRNA

0

rRNA

0

Explanation

Many types of RNA exist within cells, some are single stranded and others are double stranded. The following are among the types of single stranded RNA: mRNA (messenger RNA), tRNA (transfer RNA), and rRNA (ribosomal RNA). Messenger or mRNA carries genetic information from DNA to ribosomes for protein synthesis. Transfer or tRNA carries amino acids to ribosomes that match with mRNA codons. Last, ribosomal or rRNA codes for ribosomes, which are necessary for protein synthesis. An example of a double stranded RNA molecule is viral RNA. Viral RNA is the genetic material of many viruses and has a structure of two complementary strands.

10

Which of the following statements is false?

DNA is a polyanion, while RNA is a not

CORRECT

DNA uses thymine, while RNA uses uracil

0

DNA is typically double-stranded, while RNA is typically single-stranded

0

DNA and RNA utilize different sugars in their sugar-phosphate backbones

0

Explanation

Both DNA and RNA are polyanions. This is just a fancy way of saying that they are polymers of negatively charged molecules. The phosphate groups in the sugar-phosphate backbone account for this, as phosphate groups generally carry a charge of negative three.

DNA uses thymine and deoxyribose sugar, while RNA uses uracil and ribose sugar. While DNA is usually molded into a double-stranded helix, RNA is usually single-stranded, which allows for the binding of anticodons during translation.