Nervous System - Biology

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Question

How does the sodium-potassium pump establish a resting potential in neurons?

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Answer

The sodium potassium-pump is used in order to establish the negative resting potential in neurons. Since both sodium and potassium ions are positively charged, there needs to be more ions leaving the cell compared to ions entering. The pump accomplishes this by pumping three sodium ions out of the cell, while pumping two potassium ions into the cell. This loss of positive charge inside the cell results in the negative resting potential of neurons.

Thank about the net transfer of ions. Three positive sodium ions out of the cell for every two positive potassium ions into the cell is the same as one positive ion leaving the cell. When positive ions leave, the inside of the cell becomes more negative, helping the cell reach its resting potential of around –70mV.

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