Understanding Nephron Function - Biology

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Question

Which molecules are filtered through the glomerulus into Bowman’s capsule?

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Answer

Water, small molecules, and ions are forced through the glomerular capillaries into Bowman’s capsule in the process of filtration, largely due to the high blood pressure in the capillaries of the glomerulus. Nitrogenous compounds, namely urea, are filtered into Bowman's capsule for excretion. Glucose is also filtered into the capsule, but is reabsorbed in the proximal convoluted tubule; the presence of glucose in the final filtrate or urine can be indicative of diabetes or other maladies.

The correct answer is that two answer options are correct: small ions, glucose, amino acids, water, and nitrogenous compounds are all found in the initial filtrate.

Large molecules and cells are never filtered through the podocytes (cells lining the capsule), so we never expect to find blood cells or large blood proteins like albumin in the filtrate.

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