Pharmacokinetics
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NCLEX-PN › Pharmacokinetics
A client with a history of chronic stable angina takes nitroglycerine when needed for an acute attack. Which of the following is not associated with the administration of nitroglycerine?
The mechanism of action involves increase in cardiac contractility
To prevent degradation, nitroglycerine should be kept in a closed dark bottle.
The medication relieves pain within 3 minutes and provides relief for up to one hour
Nitroglycerine can be taken sublingually by tablet or metered spray
The patient may experience orthostatic hypotension
Explanation
Nitroglycerine is a short acting nitrate. This class of medication works by relaxing arterial and venous smooth muscle promoting vasodilation. This medication does not improve cardiac contractility.